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Saracatinib (AZD0530)

Product Specifications

CAS Number

379231-04-6

Target

Src

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) CCOC2=CC3=C (C (=C2) OC4CCOCC4) C (=NC=N3) NC5=C (C=CC6=C5OCO6) Cl

Molecular Formula

C27H32ClN5O5

Additionnal Information

Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q) . Saracatinib induces autophagy. Phase 2/3.

Storage Conditions

2 years -80 in solvent

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