What is the catalog number for DC260126?

The catalog number for DC260126 is S0742-25mg.

What sizes are available for DC260126?

DC260126 is available in the following size(s): 25 mg.

Is DC260126 in stock?

DC260126 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DC260126?

DC260126 is manufactured by Bimake.

What is the estimated delivery time for DC260126?

Estimated delivery time for DC260126 is approximately 15 business day(s), depending on your location.

DC260126

Product Specifications

CAS Number

346692-04-4

Target

GPR

Applications

GPCR & G Protein

Smiles

CCCCC1=CC=C (C=C1) NS (=O) (=O) C2=CC=C (C=C2) F

Molecular Formula

C16H18FNO2S

Additionnal Information

DC260126, a small organic antagonist for GPR40 (FFAR1), dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50=6.28, 5.96, 7.07, 4.58 μM, respectively), reduces GTP-loading and ERK1/2 phosphorylation stimulated by linoleic acid in GPR40-CHO cells, suppresses palmitic acid potentiated glucose-stimulated insulin secretion, and negatively regulates GPR40 mRNA expression induced by oleic acid in Min6 cells.