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ALR2-IN-5

ALR2-IN-5 (Compound 10a) is an inhibitor of ALR2 with an IC50 value of 99.29 nM. ALR2-IN-5 exhibits hypoglycemic effects and can be utilized in research related to diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/alr2-in-5.html

Smiles

CC1=CC=C(S(OC2=CC=C(C(C(C#N)=C(N)N3C4=NC=CS4)=C(C#N)C3=O)C=C2)(=O)=O)C=C1

Molecular Formula

C23H15N5O4S2

Molecular Weight

489.53

References & Citations

[1]Said GE, et al. Development of non-acidic 4-methylbenzenesulfonate-based aldose reductase inhibitors; Design, Synthesis, Biological evaluation and in-silicostudies. Bioorg Chem. 2024 Jul 22;151:107666.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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