2BAct
Product Specifications
CAS Number
2143542-28-1
Smiles
O=C (C (C=N1) =NC=C1C (F) F) NC (C2) (C3) CC23NC (COC (C=C4) =CC (F) =C4Cl) =O
Molecular Formula
C19H16ClF3N4O3
Additionnal Information
2BAct is a potent, orally bioavailable eIF2B activator exhibiting high selectivity (EC50 = 33 nM) . It mitigates neurological impairments induced by persistent integrated stress response. The compound demonstrates blood-brain barrier penetration with enhanced solubility and pharmacokinetic properties compared to ISRIB trans-isomer .
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
CSB-AP005251HU-01 50 µg
Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active)
Sign In for Pricing
View Details CSB-AP005251HU-02 500 µg
Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active)
Sign In for Pricing
View Details CSB-AP005251HU-03 1 mg
Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active)
Sign In for Pricing
View Details 
MBS9326478-01 48 Well
Bovine Zinc finger protein SNAI2, SNAI2 ELISA Kit
Sign In for Pricing
View Details MBS9326478-02 96 Well
Bovine Zinc finger protein SNAI2, SNAI2 ELISA Kit
Sign In for Pricing
View Details MBS9326478-03 5x 96 Well
Bovine Zinc finger protein SNAI2, SNAI2 ELISA Kit
Sign In for Pricing
View Details