2BAct
Product Specifications
CAS Number
2143542-28-1
Smiles
O=C (C (C=N1) =NC=C1C (F) F) NC (C2) (C3) CC23NC (COC (C=C4) =CC (F) =C4Cl) =O
Molecular Formula
C19H16ClF3N4O3
Additionnal Information
2BAct is a potent, orally bioavailable eIF2B activator exhibiting high selectivity (EC50 = 33 nM) . It mitigates neurological impairments induced by persistent integrated stress response. The compound demonstrates blood-brain barrier penetration with enhanced solubility and pharmacokinetic properties compared to ISRIB trans-isomer .
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2088988-01 5x 96 Tests
Human Surfactant Associated Protein D (SPD) ELISA Kit DIY Materials
Sign In for Pricing
View Details MBS2088988-02 5x 96 Tests + MBS2089471 (Support Pack 1,5x 96 Tests)
Human Surfactant Associated Protein D (SPD) ELISA Kit DIY Materials
Sign In for Pricing
View Details MBS2088988-03 10x 96 Tests
Human Surfactant Associated Protein D (SPD) ELISA Kit DIY Materials
Sign In for Pricing
View Details MBS2088988-04 10x 96 Tests + MBS2089471 (Support Pack 1, 10x 96 Tests)
Human Surfactant Associated Protein D (SPD) ELISA Kit DIY Materials
Sign In for Pricing
View Details 
MBS2089304-01 5x 96 Tests
Human Peptidase Inhibitor 3, Skin Derived (PI3) ELISA Kit DIY Materials
Sign In for Pricing
View Details