What is the catalog number for Nusinersen?

The catalog number for Nusinersen is E6580-25mg.

What sizes are available for Nusinersen?

Nusinersen is available in the following size(s): 25 mg.

Is Nusinersen in stock?

Nusinersen is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nusinersen?

Nusinersen is manufactured by Bimake.

What is the estimated delivery time for Nusinersen?

Estimated delivery time for Nusinersen is approximately 15 business day(s), depending on your location.

Nusinersen

Product Specifications

CAS Number

1258984-36-9

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Additionnal Information

Nusinersen is an 18-mer, 2′-O- (2-methoxyethyl) phosphorothioate antisense oligonucleotide used for treating spinal muscular atrophy (SMA) . It binds specifically to the intronic splice silencer N1 (ISS-N1) site in intron 7 of SMN2 pre-mRNA, blocking the binding of splicing repressors hnRNP A1/A2. This promotes inclusion of exon 7 during splicing, restoring full-length SMN protein production in SMA patients.