What is the catalog number for Safusidenib?

The catalog number for Safusidenib is E6534-25mg.

What sizes are available for Safusidenib?

Safusidenib is available in the following size(s): 25 mg.

Is Safusidenib in stock?

Safusidenib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Safusidenib?

Safusidenib is manufactured by Bimake.

What is the estimated delivery time for Safusidenib?

Estimated delivery time for Safusidenib is approximately 15 business day(s), depending on your location.

Safusidenib

Product Specifications

CAS Number

1898206-17-1

Synonyms

AB-291; DS-1001

Smiles

O=C (N1C2=CC=CC (/C=C/C (O) =O) =C2C (C) =C1) C3=C (C (C) (F) C) ON=C3C4=C (C=C (C=C4Cl) Cl) Cl

Molecular Formula

C25H18Cl3FN2O4

Additionnal Information

Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective inhibitor of mutant IDH1. It demonstrates potent inhibition against mutant IDH1 while showing minimal activity against the wild-type enzyme. The compound exhibits antitumor effects in chondrosarcoma models. In vitro assays without preincubation, safusidenib inhibits IDH1R132H and IDH1R132C with IC50 values of 15 nM and 130 nM, respectively.