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HRS-9821

Product Specifications

CAS Number

2857007-03-3

Smiles

O=C1N=C (N (CCN2C (NCC2) =O) C3=C (C) C=C (C) C=C3C) C=C4C5=C (CCN14) C=C (OC) C (OC) =C5

Molecular Formula

C28H33N5O4

Additionnal Information

PDE3/4-IN-2 (Compound 1) functions as a dual inhibitor targeting both PDE3 and PDE4 enzymes, exhibiting IC50 values of 0.13 nM for PDE3A and 50 nM for PDE4B1. This compound demonstrates potential for investigating PDE-associated pathologies including asthma, chronic obstructive pulmonary disease, sepsis, and nephritis.

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