GSK-872 hydrochloride
Product Specifications
CAS Number
2703752-81-0
Target
RIP kinase
Applications
Apoptosis
Molecular Formula
C19H17N3O2S2.ClH
Additionnal Information
GSK-872 hydrochloride is an inhibitor of RIPK3, which binds the RIP3 kinase domain with an IC50 of 1.8 nM and inhibits kinase activity with an IC50 of 1.3 nM. It exhibits the potential in alleviating early brain injury by inhibiting neuronal necroptosis and HMGB1-mediated inflammation.
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