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TYRA-300

Product Specifications

CAS Number

2800223-30-5

Target

FGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C25H24Cl2N6O3S

Additionnal Information

TYRA-300 , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.

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