What is the catalog number for BBO-8520?

The catalog number for BBO-8520 is E1968-1mg.

What sizes are available for BBO-8520?

BBO-8520 is available in the following size(s): 1 mg.

Is BBO-8520 in stock?

BBO-8520 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BBO-8520?

BBO-8520 is manufactured by Bimake.

What is the estimated delivery time for BBO-8520?

Estimated delivery time for BBO-8520 is approximately 15 business day(s), depending on your location.

BBO-8520

Product Specifications

CAS Number

2893809-51-1

Target

Ras

Applications

Apoptosis

Smiles

FC1=[C@] (C (C (F) (F) F) =CC2=C (N=C (N=C21) OC[C@@]34CCCN3C[C@@H] (C4) F) N5[C@H] (CN ([C@@H] (C5) C) C (C=C) =O) C) [C@]6=CC=C (F) C7=C6C (C#N) =C (N) S7

Molecular Formula

C35H33F6N7O2S

Additionnal Information

BBO-8520 is a covalent small molecule inhibitor that selectively targets KRAS G12C with high oral bioavailability. It functions as both a KRAS G12C (OFF) inhibitor and a blocker of KRAS G12C (ON) signaling. The compound inhibits cellular proliferation by binding to GTP-bound KRAS G12C (ON), thereby preventing RAS-RAF1 interaction and promoting the transition to the inactive (OFF) state .