What is the catalog number for TNG348?

The catalog number for TNG348 is E1955-25mg.

What sizes are available for TNG348?

TNG348 is available in the following size(s): 25 mg.

TNG348 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNG348?

TNG348 is manufactured by Bimake.

What is the estimated delivery time for TNG348?

Estimated delivery time for TNG348 is approximately 15 business day(s), depending on your location.

TNG348

Product Specifications

CAS Number

2839740-79-1

Target

JNK

Applications

MAPK

Molecular Formula

C27H23F6N9O

Additionnal Information

TNG348 is an orally bioavailable allosteric inhibitor targeting the ubiquitin-specific protease USP1. It selectively and potently blocks USP1 activity, preventing deubiquitination of proliferative PCNA and FANCD2, which disrupts DNA repair mechanisms. TNG348 demonstrates inhibitory effects against BRCA1/2-mutated and homologous recombination-deficient (HRD) breast and ovarian cancers .