What is the catalog number for Ensifentrine?

The catalog number for Ensifentrine is E1566-1g.

What sizes are available for Ensifentrine?

Ensifentrine is available in the following size(s): 1 g.

Is Ensifentrine in stock?

Ensifentrine is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ensifentrine?

Ensifentrine is manufactured by Bimake.

What is the estimated delivery time for Ensifentrine?

Estimated delivery time for Ensifentrine is approximately 15 business day(s), depending on your location.

Ensifentrine

Product Specifications

CAS Number

1884461-72-6

Synonyms

RPL-554

Target

PDE

Applications

Metabolism

Molecular Formula

C26H31N5O4

Additionnal Information

Ensifentrine (RPL-554) is a first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC50 values of 0.4 nM and 1479 nM, respectively. Ensifentrine also inhibits lipopolysaccharide-induced tumor necrosis factor alpha release from human monocytes in a concentration-dependent manner. Ensifentrine demonstrates bronchoprotective and anti-inflammatory activities and can be used for chronic obstructive pulmonary disease (COPD) research.