Icenticaftor (QBW251)
Product Specifications
CAS Number
1334546-77-8
Synonyms
NVP-QBW251
Target
CFTR
Applications
Transmembrane Transporters
Molecular Formula
C12H13F6N3O3
Additionnal Information
Icenticaftor (QBW251, NVP-QBW251) is an oral potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) channel with EC50 of 79 nM and 497 nM for F508del CFTR and G551D CFTR in Fisher Rat Thyroid (FRT) cells.
Storage Conditions
3 years -20°C powder
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