APG-2575 (lisaftoclax)
Product Specifications
CAS Number
2180923-05-9
Target
Bcl-2
Applications
Apoptosis
Smiles
ClC1=CC=C (C=C1) C2=C (CCC3 (CCC3) C2) CN4CCN (CC4) C5=CC (=C (C=C5) C (=O) N[S; v6] (=O) (=O) C6=CC (=C (NCC7COCCO7) C=C6) [N; v5] (=O) =O) OC8=CN=C9[NH]C=CC9=C8
Molecular Formula
C45H48ClN7O8S
Additionnal Information
APG-2575 (lisaftoclax) is a dual Bcl-2 and Bcl-xl inhibitor with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively.
Storage Conditions
3 years -20°C powder
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