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PY-60

Product Specifications

CAS Number

2765218-56-0

Target

YAP

Applications

Hippo

Molecular Formula

C16H15N3O2S

Additionnal Information

PY-60 is a small-molecule activator of the transcriptional coactivator Yes-associated protein (YAP) with EC50 of 1.6 μM, which acts by inhibiting a central scaffolding protein in the Hippo pathway, Annexin A2. It promotes the regenerative repair of cutaneous wounds in pig and human models.
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