Ac-FLTD-CMK
Product Specifications
CAS Number
2376255-48-8
Target
Pyroptosis
Applications
Apoptosis
Smiles
CC (C) CC (NC (=O) C (CC1=CC=CC=C1) NC (C) =O) C (=O) NC (C (C) O) C (=O) NC (CC (O) =O) C (=O) CCl
Molecular Formula
C26H37ClN4O8
Additionnal Information
Ac-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively.
Storage Conditions
3 years -20°C powder
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