IXA4
Product Specifications
CAS Number
1185329-96-7
Target
IRE1
Applications
ER stress & UPR
Smiles
CN (CCOC1=CC=C (C) C=C1) C (=O) C[N]2C=C (NC (=O) CCOC3=CC=CC=C3) C=N2
Molecular Formula
C24H28N4O4
Additionnal Information
IXA4, a highly selective, non-toxic IRE1/XBP1s activator, activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways, and reduces secretion of amyloid precursor protein (APP) through IRE1 activation, preventing APP-associated mitochondrial dysfunction.
Storage Conditions
3 years -20°C powder
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