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Fatostatin

Product Specifications

CAS Number

125256-00-0

Synonyms

125B11

Target

SREBP

Applications

Metabolism

Smiles

CCCC1=CC (=CC=N1) C2=NC (=CS2) C3=CC=C (C) C=C3

Molecular Formula

C18H18N2S

Additionnal Information

Fatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells.

Storage Conditions

3 years -20°C powder

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