ME-344
Product Specifications
CAS Number
1374524-68-1
Target
OXPHOS
Applications
Apoptosis
Molecular Formula
C22H20O4
Additionnal Information
ME-344 is a synthetic metabolite of NV-128, a potent inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) complex I, disrupting ATP generation and oxygen consumption. It also inhibits mTOR by downregulating the AKT/mTOR pathway, exhibiting anticancer activity by inhibiting cell growth and viability in leukemia cell lines with IC50 values of 70–260 nM.
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