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SZL P1-41

Product Specifications

CAS Number

222716-34-9

Target

E3 Ligase

Applications

Ubiquitin

Smiles

CCC1=C (O) C (=C2OC=C (C (=O) C2=C1) C3=NC4=C (S3) C=CC=C4) CN5CCCCC5

Molecular Formula

C24H24N2O3S

Additionnal Information

SZL P1-41 (compound #25) is a specific inhibitor of S-phase kinase-associated protein 2 (Skp2) that indeed binds to Skp2, prevents Skp2-Skp1 interaction and inhibits Skp2 SCF E3 ligase activity, which consequently suppresses survival of cancer cells and cancer stem cells. SZL P1-41 causes higher apoptosis rates in cancer cells.

Storage Conditions

3 years -20°C powder

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