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Limantrafin (CB-103)

Product Specifications

CAS Number

218457-67-1

Target

Notch

Applications

Neuronal Signaling

Smiles

CC (C) (C) C1=CC=C (OC2=CC=C (N) C=N2) C=C1

Molecular Formula

C15H18N2O

Additionnal Information

Limantrafin (CB-103) is an orally active inhibitor of the Notch transcription activation complex. CB-103 produces Notch loss-of-function phenotypes in flies and mice and inhibits the growth of human breast cancer and leukemia xenografts.

Storage Conditions

3 years -20°C powder

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