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Apostatin-1 (Apt-1)

Product Specifications

CAS Number

2559703-06-7

Target

TRADD

Applications

Apoptosis

Smiles

CN1CCN=C1SC (C (=O) NC2CCCCCC2) C3=CC=CC=C3

Molecular Formula

C19H27N3OS

Additionnal Information

Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N) . Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.

Storage Conditions

3 years -20°C powder

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