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Tapinarof

Product Specifications

CAS Number

79338-84-4

Synonyms

GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505

Target

AhR

Applications

Immunology & Inflammation

Smiles

CC (C) C1=C (O) C=C (\C=C\C2=CC=CC=C2) C=C1O

Molecular Formula

C17H18O2

Additionnal Information

Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.

Storage Conditions

3 years -20°C powder

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