IFSP1
Product Specifications
CAS Number
150651-39-1
Target
Ferroptosis
Applications
Apoptosis
Smiles
CC1=CC=C (C=C1) C2=C (C3=NC4=CC=CC=C4N3C (=C2C#N) N) C#N
Molecular Formula
C20H13N5
Additionnal Information
IFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1/AIFM2) with EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout Pfa1 and HT1080 cells that overexpresses FSP1.Solutions are unstable and should be fresh-prepared.
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