UNC2025
Product Specifications
CAS Number
1429881-91-3
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CCCCNC1=NC=C2C (=CN (C2=N1) C3CCC (CC3) O) C4=CC=C (C=C4) CN5CCN (CC5) C
Molecular Formula
C28H40N6O
Additionnal Information
UNC2025 is a potent and orally active dual inhibitor of FLT3 and MER with IC50 of 0.35 nM and 0.46 nM, respectively. UNC2025 also inhibits AXL, TRKA, TRKC, QIK, TYRO3, SLK, NuaK1, Kit (c-Kit) and Met (c-Met) with IC50 of 1.65 nM, 1.67 nM, 4.38 nM, 5.75 nM, 5.83 nM, 6.14 nM, 7.97 nM, 8.18 nM and 364 nM, respectively.
Storage Conditions
3 years -20°C powder
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