UNC6852
Product Specifications
CAS Number
2688842-08-0
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC=N1) C2=CC=C (CNC (=O) C3CC (O) CN3C (=O) C (NC (=O) CCCNC (=O) C4=CC=C (C=C4) C5=CN=C (NCC6=CC=CO6) [N]7C=NN=C57) C (C) (C) C) C=C2
Molecular Formula
C43H48N10O6S
Additionnal Information
UNC6852 is a selective degrader that targets polycomb repressive complex 2 (PRC2) with IC50 of 247 nM for EED. UNC6852 is based on PROTAC and contains an EED226-derived ligand and a ligand for VHL.
Storage Conditions
3 years -20°C powder
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