Enarodustat (JTZ-951)
Product Specifications
CAS Number
1262132-81-9
Target
HIF
Applications
Angiogenesis
Smiles
C1=CC=C (C=C1) CCC2=CC (=O) C (=C3N2NC=N3) C (=O) NCC (=O) O
Molecular Formula
C17H16N4O4
Additionnal Information
Enarodustat (JTZ-951) is a potent and orally active HIF prolyl hydroxylase inhibitor with IC50 of 0.22 μM for PHD2 and EC50 of 5.7 μM for EPO release from Hep3B cells. Enarodustat has the potential for the treatment of renal anemia.
Storage Conditions
3 years -20°C powder
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