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Enarodustat (JTZ-951)

Product Specifications

CAS Number

1262132-81-9

Target

HIF

Applications

Angiogenesis

Smiles

C1=CC=C (C=C1) CCC2=CC (=O) C (=C3N2NC=N3) C (=O) NCC (=O) O

Molecular Formula

C17H16N4O4

Additionnal Information

Enarodustat (JTZ-951) is a potent and orally active HIF prolyl hydroxylase inhibitor with IC50 of 0.22 μM for PHD2 and EC50 of 5.7 μM for EPO release from Hep3B cells. Enarodustat has the potential for the treatment of renal anemia.

Storage Conditions

3 years -20°C powder

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