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PF-06821497

Product Specifications

CAS Number

1844849-10-0

Target

EZH1/2

Applications

Epigenetics

Smiles

CC1=CC (=C (C (=O) N1) CN2CCC3=C (C=C (C (=C3C2=O) Cl) C (C4COC4) OC) Cl) OC

Molecular Formula

C22H24Cl2N2O5

Additionnal Information

PF-06821497 is a selective and orally active inhibitor of Zeste Homolog 2 (EZH2) with a Ki value <0.1 nM against mutant Y641N EZH2. It exhibits robust tumor growth inhibition.

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