CBR-5884
Product Specifications
CAS Number
681159-27-3
Target
Dehydrogenase
Applications
Metabolism
Smiles
CCOC (=O) C1=C (C (=C (S1) NC (=O) C2=CC=CO2) SC#N) C
Molecular Formula
C14H12N2O4S2
Additionnal Information
CBR-5884 is a selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and was selectively toxic to cancer cell lines with high serine biosynthetic activity.
Storage Conditions
3 years -20°C powder
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