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CBR-5884

Product Specifications

CAS Number

681159-27-3

Target

Dehydrogenase

Applications

Metabolism

Smiles

CCOC (=O) C1=C (C (=C (S1) NC (=O) C2=CC=CO2) SC#N) C

Molecular Formula

C14H12N2O4S2

Additionnal Information

CBR-5884 is a selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and was selectively toxic to cancer cell lines with high serine biosynthetic activity.

Storage Conditions

3 years -20°C powder

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