Donafenib (Sorafenib D3)
Product Specifications
CAS Number
1130115-44-4
Synonyms
Bay 43-9006 D3, CM-4307
Target
Raf
Applications
MAPK
Smiles
CNC (=O) C1=NC=CC (=C1) OC2=CC=C (C=C2) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F
Molecular Formula
C21H13D3ClF3N4O3
Additionnal Information
Donafenib (Sorafenib D3, Bay 43-9006 D3, CM-4307) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 15 nM, 20 nM and 22 nM for Raf-1, mVEGFR-2, mVEGFR-3 and B-RAF, respectively.
Storage Conditions
3 years -20°C powder
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