BMS-1001
Product Specifications
CAS Number
2113650-03-4
Target
PD-1/PD-L1
Applications
Apoptosis
Smiles
CC1=CC (=C (C=C1OCC2=C (C (=CC=C2) C3=CC4=C (C=C3) OCCO4) C) OCC5=CC (=CC=C5) C#N) CNC (CO) C (=O) O
Molecular Formula
C35H34N2O7
Additionnal Information
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM. BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes.
Storage Conditions
3 years -20°C powder
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