Lurbinectedin
Product Specifications
CAS Number
497871-47-3
Synonyms
PM-1183, LY-01017, Tryptamicidin, PM01183
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
CC1=CC2=C (C3C4C5C6=C (C (=C7C (=C6C (N4C (C (C2) N3C) O) COC (=O) C8 (CS5) C9=C (CCN8) C2=C (N9) C=CC (=C2) OC) OCO7) C) OC (=O) C) C (=C1OC) O
Molecular Formula
C41H44N4O10S
Additionnal Information
Lurbinectedin, a DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity. Lurbinectedin inhibits RMG1 and RMG2 cell growth with IC50 of 1.25 nM and 1.16 nM, respectively.
Storage Conditions
3 years -20°C powder
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