Triptophenolide
Product Specifications
CAS Number
74285-86-2
Synonyms
Hypolide
Target
Androgen Receptor
Applications
Endocrinology & Hormones
Smiles
CC (C) C1=C (C2=C (C=C1) C3 (CCC4=C (C3CC2) COC4=O) C) O
Molecular Formula
C20H24O3
Additionnal Information
Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
Storage Conditions
3 years -20°C powder
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