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Gambogenic acid

Product Specifications

CAS Number

173932-75-7

Target

FGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C38H46O8

Additionnal Information

Gambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.

Storage Conditions

3 years -20°C powder

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