Gambogenic acid
Product Specifications
CAS Number
173932-75-7
Target
FGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C38H46O8
Additionnal Information
Gambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.
Storage Conditions
3 years -20°C powder
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