Revumenib (SNDX-5613)
Product Specifications
CAS Number
2169919-21-3
Target
MLL
Applications
Epigenetics
Smiles
CCN (C (C) C) C (=O) C1=C (OC2=CN=CN=C2N3CC4 (CCN (CC4) CC5CCC (CC5) N[S] (=O) (=O) CC) C3) C=CC (=C1) F
Molecular Formula
C32H47FN6O4S
Additionnal Information
Revumenib (SNDX-5613) is a potent and selective inhibitor of menin-MLL binding with a Ki of 0.15 nM. SNDX-5613 shows anti-proliferative activity against multiple cell lines harboring MLLr translocations (MV4;11, RS4;11, MOLM-13, KOPN-8) with IC50 values ranging from 10-20 nM.
Storage Conditions
3 years -20°C powder
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