BRD3308
Product Specifications
CAS Number
1550053-02-5
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CC (=O) NC1=CC=C (C=C1) C (=O) NC2=C (C=C (C=C2) F) N
Molecular Formula
C15H14FN3O2
Additionnal Information
BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.
Storage Conditions
3 years -20°C powder
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