G10 (STING agonist-1)
Product Specifications
CAS Number
702662-50-8
Target
IFN
Applications
Immunology & Inflammation
Smiles
C1C (=O) N (C2=C (S1) C=CC (=C2) C (=O) NCC3=CC=CO3) CC4=C (C=CC=C4Cl) F
Molecular Formula
C21H16ClFN2O3S
Additionnal Information
G10 (STING agonist-1) is a novel human-specific STING agonist that triggers IFN regulatory factor 3 (IRF3) / type I interferon (IFN) -associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM.
Storage Conditions
3 years -20°C powder
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