TED-347

Product Specifications

CAS Number

2378626-29-8

Target

YAP

Applications

Hippo

Smiles

C1=CC=C (C (=C1) C (=O) CCl) NC2=CC=CC (=C2) C (F) (F) F

Molecular Formula

C15H11ClF3NO

Additionnal Information

TED-347 is a potent, irreversible, covalent and allosteric inhibitor of the TEAD⋅Yap protein-protein interaction. TED-347 inhibits TEAD4⋅Yap1 protein-protein interaction with an apparent EC50 of 5.9 μM.

Storage Conditions

3 years -20°C powder

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