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VLX600

Product Specifications

CAS Number

327031-55-0

Target

OXPHOS

Applications

Apoptosis

Smiles

CC1=C2C (=CC=C1) C3=C (N2) N=C (N=N3) NN=C (C) C4=CC=CC=N4

Molecular Formula

C17H15N7

Additionnal Information

VLX600 is a novel iron-chelating inhibitor of oxidative phosphorylation (OXPHOS), potentiates the effect of radiation in tumor spheroids in a synergistic manner. VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvation. VLX600 induces autophagy and mitochondrial inhibition with antitumor activity.

Storage Conditions

3 years -20°C powder

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