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Mizagliflozin (KWA 0711)

Product Specifications

CAS Number

666843-10-3

Target

SGLT

Applications

GPCR & G Protein

Smiles

CC1=C (C=CC (=C1) OCCCNCC (C) (C) C (=O) N) CC2=C (NN=C2OC3C (C (C (C (O3) CO) O) O) O) C (C) C

Molecular Formula

C28H44N4O8

Additionnal Information

Mizagliflozin (KWA 0711) is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation.

Storage Conditions

3 years -20°C powder

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