Taletrectinib (DS-6051b)
Product Specifications
CAS Number
1505515-69-4
Synonyms
AB-106
Target
ROS1
Applications
Protein Tyrosine Kinase
Smiles
CC (COC1=CC=C (C=C1) C2=CN=C3N2N=C (C=C3) NC (C) C4=CC (=CC=C4) F) N.C (CCC (=O) O) CC (=O) O
Molecular Formula
C29H34FN5O5
Additionnal Information
Taletrectinib (DS-6051b, AB-106) is a new-generation selective ROS1/NTRK inhibitor with ic50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM for ROS1, NTRK1, NTRK2 and NTRK3, respectively.
Storage Conditions
3 years -20°C powder
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