MLT-748
Product Specifications
CAS Number
1832578-30-9
Target
MALT
Applications
NF-κB
Smiles
CC (C (C1=C (C=NC2=CC (=NN21) Cl) NC (=O) NC3=CC (=C (N=C3) N4N=CC=N4) Cl) OC) OC
Molecular Formula
C19H19Cl2N9O3
Additionnal Information
MLT-748 is a potent, selective and allosteric inhibitor of MALT1 with IC50 of 5 nM, binding at the interface between the caspase and immunoglobulin (Ig3) domains by displacing Trp580 and locking the catalytic site in an inactive state.
Storage Conditions
3 years -20°C powder
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