What is the catalog number for SR-4835?

The catalog number for SR-4835 is S8894-1g.

What sizes are available for SR-4835?

SR-4835 is available in the following size(s): 1 g.

SR-4835 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SR-4835?

SR-4835 is manufactured by Bimake.

What is the estimated delivery time for SR-4835?

Estimated delivery time for SR-4835 is approximately 15 business day(s), depending on your location.

SR-4835

Product Specifications

CAS Number

2387704-62-1

Target

CDK

Applications

Cell Cycle

Smiles

CN1C=C (C=N1) N2C=NC3=C (N=C (N=C32) N4CCOCC4) NCC5=NC6=CC (=C (C=C6N5) Cl) Cl

Molecular Formula

C21H20Cl2N10O

Additionnal Information

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.