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JHU395

Product Specifications

CAS Number

2079938-92-2

Target

Glutaminase

Applications

Proteases

Smiles

CC (C) OC (=O) C (CCC (=O) C=[N+]=[N-]) NC (=O) OC (OC (=O) C (C) (C) C) C1=CC=CC=C1

Molecular Formula

C22H29N3O7

Additionnal Information

JHU395 is a novel orally bioavailable GA (glutamine antagonists) prodrug designed to circulate inert in plasma, but permeate and release active GA within target tissues. JHU395 delivers active GA to malignant peripheral nerve sheath tumor (MPNST), and significantly inhibits tumor growth without observed toxicity.

Storage Conditions

2 years -20°C liquid

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