JHU-083
Product Specifications
CAS Number
1998725-11-3
Synonyms
Ethyl 2- (2-Amino-4-methylpentanamido) -DON
Target
Glutaminase
Applications
Proteases
Smiles
CCOC (=O) C (CCC (=O) C=[N+]=[N-]) NC (=O) C (CC (C) C) N
Molecular Formula
C14H24N4O4
Additionnal Information
JHU-083 (Ethyl 2- (2-Amino-4-methylpentanamido) -DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are unstable and should be fresh-prepared.
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