JHU-083

Product Specifications

CAS Number

1998725-11-3

Synonyms

Ethyl 2- (2-Amino-4-methylpentanamido) -DON

Target

Glutaminase

Applications

Proteases

Smiles

CCOC (=O) C (CCC (=O) C=[N+]=[N-]) NC (=O) C (CC (C) C) N

Molecular Formula

C14H24N4O4

Additionnal Information

JHU-083 (Ethyl 2- (2-Amino-4-methylpentanamido) -DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are unstable and should be fresh-prepared.